Losing weight is not as easy as it is usually advertised. In 2012, for BBC Two's Horizon, Michael Mosley, a doctor and journalist took this on further, with a personal investigation into fasting as a way to live longer, look younger and lose weight." It generated huge media interest and the multimillion-selling Fast Diet or 5:2 — intermittent fasting on two days out of seven — was the result.

The study, led by University of Freiburg, was published in The BMJ and also highlighted a stark lack research on the long-term health effects of sweeteners when taken over years or decades — in part due to the difficulty of enlisting people to take part in such a study.

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