Weight loss for women over 50 isn't the same as when you were in your 20s and 30s. According to the National Center for Complementary and Integrative Health , there isn't enough evidence to support the use of bitter orange. What's more, the use of the supplement has been associated with chest pain, increased blood pressure and heart rate, and anxiety and there are reports that they may have resulted in harmful side effects in people who took bitter orange alone or combined with stimulants (such as caffeine), medications, and supplements.
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